The Effect of Specific Oral Nutritional Supplements Compared to Tea with Sugar on Gastric Emptying Time, Blood Glucose Level, and Hunger Response in Healthy Adults

Abstract

Introduction: The objective of this study was to compare gastric emptying time, hunger response, and blood glucose level after drinking specific oral nutritional supplements (S-ONS) to tea with sugar in healthy adults. Methods: This study was a clinical, parallel, random allocation, and single-blind trial. This study was conducted at Cipto Mangunkusumo General Hospital, Jakarta. The subjects were 12 healthy adults divided into 2 groups: intervention group (n = 6) and control group (n = 6). Patients in the intervention group received 200 mL S-ONS (200 kcal, 18% protein, 20% fat and 62% carbohydrate) and control group received 200 mL of tea with 10 grams of sugar (40 kcal). Gastric volume was measured using 2D-sonography every 30 minutes. Blood glucose level was measured using blood peripheral sample. Hunger response was measured using visual analog scale (VAS). Results: Gastric emptying time in the intervention group was <90 minutes, and in the control group <60 minutes. Blood glucose level was increased in the intervention group and decreased in control group. Hunger response was decreased in intervention group and increased in control group. Conclusion: Gastric emptying time after either drinking S-ONS and drinking tea with sugar in healthy adults subjects were less than 2 hours. Patients receiving S-ONS had significantly higher blood glucose level and were less hungry than the control group.

Keywords

• ONS, gastric emptying time, blood-glucose level, hunger response