Biology (Jul 2022)

Application of Micro-Computed Tomography for the Estimation of the Post-Mortem Interval of Human Skeletal Remains

  • Verena-Maria Schmidt,
  • Philipp Zelger,
  • Claudia Woess,
  • Anton K. Pallua,
  • Rohit Arora,
  • Gerald Degenhart,
  • Andrea Brunner,
  • Bettina Zelger,
  • Michael Schirmer,
  • Walter Rabl,
  • Johannes D. Pallua

DOI
https://doi.org/10.3390/biology11081105
Journal volume & issue
Vol. 11, no. 8
p. 1105

Abstract

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It is challenging to estimate the post-mortem interval (PMI) of skeletal remains within a forensic context. As a result of their interactions with the environment, bones undergo several chemical and physical changes after death. So far, multiple methods have been used to follow up on post-mortem changes. There is, however, no definitive way to estimate the PMI of skeletal remains. This research aimed to propose a methodology capable of estimating the PMI using micro-computed tomography measurements of 104 human skeletal remains with PMIs between one day and 2000 years. The present study indicates that micro-computed tomography could be considered an objective and precise method of PMI evaluation in forensic medicine. The measured parameters show a significant difference regarding the PMI for Cort Porosity p p > 0.001, Mean1 p > 0.001 and Mean2 p > 0.005. Using a machine learning approach, the neural network showed an accuracy of 99% for distinguishing between samples with a PMI of less than 100 years and archaeological samples.

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