Dihydropyridine calcium antagonists: conscious choice

Abstract

This article contains information concerning the aspects of pharmacokinetics and pharmacodynamics of dihydropyridine calcium antagonists. The authors have discussed the evidence-based amlodipine treatment of arterial hypertension, ischemic heart disease and chronic heart failure. The authors present the comparison of the efficacy, safety and application characteristics of the different dihydropyridine calcium antagonists that can be used in specific clinical cases.

Keywords

• arterial hypertension
• angina
• atherosclerosis
• calcium antagonists
• amlodipine