Acta Biomedica Scientifica (Nov 2017)

TO THE SELECTION OF BONE CAVITY FILLING MATERIAL FOR PATIENTS WITH CHRONIC OSTEOMYELITIS

  • A. S. Shtofin,
  • M. B. Shchegolev,
  • P. V. Trushin,
  • V. A. Golovnev,
  • A. V. Golovnev,
  • S. G. Shtofin

DOI
https://doi.org/10.12737/article_5a0a8717eae886.30878537
Journal volume & issue
Vol. 2, no. 6
pp. 76 – 81

Abstract

Read online

The research covered 83 patients with chronic osteomyelitis, 55 patients underwent the original operation of single stage sequestrectomy and grafting the residual bone cavity with fine-grain titanium nickelide. This method of treatment has demonstrated its effectiveness in the early rehabilitation period, as well as in the observation in a remote period of time. Clinical effects were characterized by the absence of relapses of chronic osteomyelitis in 94.6 % of patients during the follow-up period. The simulating effect of titanium nickelide in the formation of trabecular bone tissue was experimentally based on 20 animals (dogs). Thus, clinic-experimental research showed that porous titanium nickelide is a perspective material and can be used for different skeletal pathologies. Using it as bone cavity filling in the experiment resulted in an accelerated (3 months earlier) formation of bone organotypic regenerate. The use of bio-compatible fine-grain titanium nickelide contributes into rapid and efficient completion of inflammation process in bone tissue, simplifies the methodology, reduces the time of operation and the time of rehabilitation period and, as a result, increases the efficiency of treating patients with chronic osteomyelitis.

Keywords