Emerging Infectious Diseases (Oct 2007)

Super-Sentinel Chickens and Detection of Low-Pathogenicity Influenza Virus

  • Philip I. Marcus,
  • Theodore Girshick,
  • Louis van der Heide,
  • Margaret J. Sekellick

DOI
https://doi.org/10.3201/eid1310.061552
Journal volume & issue
Vol. 13, no. 10
pp. 1608 – 1610

Abstract

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Chicken interferon-α administered perorally in drinking water acts on the oropharyngeal mucosal system as an adjuvant that causes chickens to rapidly seroconvert after natural infection by low-pathogenicity Influenza virus. These chickens, termed super sentinels, can serve as sensitive early detectors of clinically inapparent infections.

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