Iron deficiencies in obstetric-gynecologic practice

Abstract

Ar.A. Mikhelson, E.Yu. Lebedenko, O.V. Gayda, Al.A. Mikhelson, T.E. Feoktistova, A.M. Mikhelson Rostov State Medical University, Rostov-on-Don, Russian Federation Deficiency or excess of microelements and vitamins significantly affects the vital activity at each step of human life. This is particularly significant during pregnancy because of immediate and long-term effects on the fetus and newborn. Iron is one of the essential microelements and plays an important role in the mechanisms of biological oxidation. Iron metabolism in the human body is quite complex and impossible without synergy with other metals and vitamins. Iron is most closely related to folic acid and is critical for many vital processes, including embryogenesis. Considering that iron and folic acid deficiencies (leading to anemias in extreme cases) negatively affect pregnancy course, its favorable outcome, and prognosis for a newborn, these conditions are to be addressed. Medications are diverse, they should be selected based on the specificity of iron and folic acid metabolism. Among preparations currently available in Russia, combined ones best meet the requ irements (iron valence, iron compounds, association with synergid components, dosage form). Keywords: iron, folic acid, iron-deficiency anemia, folate-deficiency anemia, therapy, combined preparations. For citation: Mikhelson Ar.A., Lebedenko E.Yu., Gayda O.V. et al. Iron deficiencies in obstetric-gynecologic practice. Russian Journal of Woman and Child Health. 2022;5(2):129–137 (in Russ.). DOI: 10.32364/2618-8430-2022-5-2-129-137.