Nature Communications (Dec 2022)

Temperature-adaptive hydrogel optical waveguide with soft tissue-affinity for thermal regulated interventional photomedicine

  • Guoyin Chen,
  • Kai Hou,
  • Nuo Yu,
  • Peiling Wei,
  • Tao Chen,
  • Caihong Zhang,
  • Shun Wang,
  • Hongmei Liu,
  • Ran Cao,
  • Liping Zhu,
  • Benjamin S. Hsiao,
  • Meifang Zhu

DOI
https://doi.org/10.1038/s41467-022-35440-w
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 9

Abstract

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Light penetration and overheating are major issues facing the application of photothermal therapy. Here, the authors develop a temperature responsive hydrogel optical waveguide for controlled delivery of light to deep tumours and demonstrate biocompatibility and temperature responsive phototherapy in vivo