Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul (Oct 2000)
The comparison of intrauterine insemination (IUI) in infertile couples due to male factor with infertility that is unexplained
Abstract
Objective: Intrauterine insemination is one of the treatment methods for infertility. This study assesses the results of IUI in two groups, which include of male factor infertility and infertility that is unexplained. Methods: This study was done in the form of census on the bases of data in 223 files of infertile patients who referred to Fatemeh Zahra fertility and infertility center of Babol. These data showed that clomiphene alone or clomiphene with HMG was used to induce ovulation for every patient. Then they were followed by vaginal sonography and after having at least one follicle (18mm or more) they received HCG and finally after two weeks βHCG was done for pregnancy test. Then the analysis of obtained results was done by Chi-square and T-test. Findings: 223 patients undergone with a total of 419 times of IUI. Of these, 134 had a male factor and underwent 234 IUIs, as a result 15 women were successfully conceived (11.2% for every patient and 6.4% for every menstrual cycle). 89 patients in unexplained infertile group underwent 185 IUIs resulting in 4 cases of pregnancy and pregnancy rate of every patient was 4.2% and for every menstrual cycle 2.1%. In 50 infertile patients with male factor whose sperm counts were under 10 millions/ml. (Severe oligospermia) there was only one pregnancy (0.7%). Conclusion: In treatment of infertile patients with male factor, specially those who without a severe oligospermia compared with unexplained infertile patients, IUI and COH (Controlled ovarian hyperstimulation) was more successful.
