Nature Communications (Nov 2021)

A benchmark study of simulation methods for single-cell RNA sequencing data

  • Yue Cao,
  • Pengyi Yang,
  • Jean Yee Hwa Yang

DOI
https://doi.org/10.1038/s41467-021-27130-w
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 12

Abstract

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Simulation is useful for developing and evaluating computational methods. Here, the authors develop a comprehensive evaluation framework, SimBench, to benchmark Single-cell RNA-seq simulation methods through a diverse collection of experimental datasets.