Unleashing the power of energy storage: Engineering β-oxidation pathways for polyketide production

Bin Wang; Huimin Zhao

Synthetic and Systems Biotechnology (Mar 2020)

Unleashing the power of energy storage: Engineering β-oxidation pathways for polyketide production

Bin Wang,
Huimin Zhao

Affiliations

Bin Wang: Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA
Huimin Zhao: Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA; Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA; Corresponding author. Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.

Journal volume & issue: Vol. 5, no. 1
pp. 21 – 22

Abstract

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Overproduction of polyketides has been a challenge for metabolic engineering for decades. However, recent studies have demonstrated that in both native host and heterologous host, engineering β -oxidation pathways can lead to dramatic improvement of polyketide production. Keywords: Polyketide, Beta-oxidation pathway, Metabolic engineering, Triacylglycerols

Published in Synthetic and Systems Biotechnology

ISSN: 2405-805X (Online)
Publisher: KeAi Communications Co., Ltd.
Country of publisher: China
LCC subjects: Technology: Chemical technology: Biotechnology; Science: Biology (General)
Website: https://www.keaipublishing.com/en/journals/synthetic-and-systems-biotechnology/

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