Communications Biology (Jun 2021)
Predicting the probability of death using proteomics
- Thjodbjorg Eiriksdottir,
- Steinthor Ardal,
- Benedikt A. Jonsson,
- Sigrun H. Lund,
- Erna V. Ivarsdottir,
- Kristjan Norland,
- Egil Ferkingstad,
- Hreinn Stefansson,
- Ingileif Jonsdottir,
- Hilma Holm,
- Thorunn Rafnar,
- Jona Saemundsdottir,
- Gudmundur L. Norddahl,
- Gudmundur Thorgeirsson,
- Daniel F. Gudbjartsson,
- Patrick Sulem,
- Unnur Thorsteinsdottir,
- Kari Stefansson,
- Magnus O. Ulfarsson
Affiliations
- Thjodbjorg Eiriksdottir
- deCODE Genetics/Amgen, Inc.
- Steinthor Ardal
- deCODE Genetics/Amgen, Inc.
- Benedikt A. Jonsson
- deCODE Genetics/Amgen, Inc.
- Sigrun H. Lund
- deCODE Genetics/Amgen, Inc.
- Erna V. Ivarsdottir
- deCODE Genetics/Amgen, Inc.
- Kristjan Norland
- deCODE Genetics/Amgen, Inc.
- Egil Ferkingstad
- deCODE Genetics/Amgen, Inc.
- Hreinn Stefansson
- deCODE Genetics/Amgen, Inc.
- Ingileif Jonsdottir
- deCODE Genetics/Amgen, Inc.
- Hilma Holm
- deCODE Genetics/Amgen, Inc.
- Thorunn Rafnar
- deCODE Genetics/Amgen, Inc.
- Jona Saemundsdottir
- deCODE Genetics/Amgen, Inc.
- Gudmundur L. Norddahl
- deCODE Genetics/Amgen, Inc.
- Gudmundur Thorgeirsson
- deCODE Genetics/Amgen, Inc.
- Daniel F. Gudbjartsson
- deCODE Genetics/Amgen, Inc.
- Patrick Sulem
- deCODE Genetics/Amgen, Inc.
- Unnur Thorsteinsdottir
- deCODE Genetics/Amgen, Inc.
- Kari Stefansson
- deCODE Genetics/Amgen, Inc.
- Magnus O. Ulfarsson
- deCODE Genetics/Amgen, Inc.
- DOI
- https://doi.org/10.1038/s42003-021-02289-6
- Journal volume & issue
-
Vol. 4,
no. 1
pp. 1 – 11
Abstract
Eiriksdottir et al. use a temporal proteomic dataset from over 22,000 Icelandic individuals to identify predictors and predict all-cause mortality. Their findings suggest that the plasma proteome may be of value in general health screening for risk of death.