Clinical Ophthalmology (Mar 2024)

Clinical Results of a Trifocal Toric Intraocular Lens Using the Holladay Total Surgically Induced Astigmatism Formula for Correcting Low Corneal Astigmatism in Japanese Patients

  • Bissen-Miyajima H,
  • Ota Y,
  • Yaguchi S,
  • Nakamura K,
  • Sasaki N

Journal volume & issue
Vol. Volume 18
pp. 755 – 763

Abstract

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Hiroko Bissen-Miyajima,1 Yuka Ota,1 Saori Yaguchi,1 Kunihiko Nakamura,1 Noriyuki Sasaki2 1Department of Ophthalmology, Tokyo Dental College Suidobashi Hospital, Tokyo, Japan; 2Alcon Japan Ltd, Tokyo, JapanCorrespondence: Hiroko Bissen-Miyajima, Department of Ophthalmology, Tokyo Dental College, Suidobashi Hospital, Kandamisaki‑cho 2‑9‑18, Chiyoda‑ku, Tokyo, 101‑0061, Japan, Tel +81-3-5275-1856, Email [email protected]: To evaluate the effectiveness and safety of the AcrySof IQ PanOptix toric intraocular lens (IOL) with cylinder power of 1.0 D (TFNT20) in a Japanese population with low corneal astigmatism and compare with historical control data for nontoric IOLs.Setting: Tokyo Dental College Suidobashi Hospital, Tokyo, Japan.Design: Prospective, single-center study.Methods: Patients ≥ 20 years old received TFNT20 IOL in at least 1 eye based on Alcon Toric calculator (Holladay Total surgically induced astigmatism). Effectiveness endpoints included the percentage of eyes with refractive cylinder ≤ 0.25 D at 30– 60 days after surgery, which was compared with a historical control threshold rate of 29.2% for nontoric IOLs and refractive cylinder ≤ 0.50 D. Monocular uncorrected distance visual acuity (UDVA; 5 m), uncorrected intermediate visual acuity (UIVA; 60 cm), uncorrected near visual acuity (UNVA; 40 cm), and adverse events were evaluated.Results: Of 41 eyes implanted with TFNT20 IOLs, 37 eyes (90%) achieved refractive cylinder ≤ 0.25 D at 30– 60 days after surgery, demonstrating the superiority of TFNT20 compared with historical data (P< 0.0001). Refractive cylinder of ≤ 0.50 D was achieved by 41 eyes (100%). At 30– 60 days, mean ± SD monocular CDVA was − 0.15 ± 0.07 logMAR, UDVA was − 0.09 ± 0.09 logMAR, UIVA was − 0.00 ± 0.07 logMAR, and UNVA was 0.03 ± 0.07 logMAR. Six eyes (15%) had elevated postoperative intraocular pressure, which returned to normal and was not device-related.Conclusion: TFNT20 IOLs successfully reduced postoperative refractive cylinder and provided good distance, intermediate, and near uncorrected VAs in Japanese patients with low corneal astigmatism.Keywords: trifocal IOL, toric IOL, low corneal astigmatism, toric calculator, visual acuity

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