Кардиоваскулярная терапия и профилактика (Feb 2017)

EFFECTIVENESS OF 12-WEEK OUTPATIENT PHYSICAL REHABILITATION OF PATIENTS AFTER NON-ST-ELEVATION ACUTE CORONARY SYNDROME WITH PERCUTANEOUS CORONARY INTERVENTION ON INFARCTION-RELEVANT ARTERY

  • К. A. Volodina,
  • R. М. Linchak,
  • E. Е. Achkasov,
  • E. N. Alaeva,
  • N. V. Tkhay,
  • О. V. Bulgakova

DOI
https://doi.org/10.15829/1728-8800-2017-1-61-66
Journal volume & issue
Vol. 16, no. 1
pp. 61 – 66

Abstract

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Aim. To assess the efficacy of physical cardiorehabilitation in patients with acute coronary syndrome non-ST-elevation (NSTEACS) and percutaneous coronary intervention (PCI) on infarction-relevant artery.Material and methods. To the prospective study, 35 patients included — mean age 57,9±9,7 y.o.; 78% males, 22% females after NSTEACS with urgent PCI on symptom-dependent artery and noncomplicated post-surgery period. Time of inclusion into the study was 2-8 weeks after ACS onset. At 1 and 12 weeks of cardiorehabilitation programs there was functional (echocardiography, electrocardiography, exercise testing) and laboratory diagnostics (lipids and chemistry). For 12 weeks the participants visited 3 times per weeks the standard cardorehabilitation trainings.Results. After the cardiorehabilitation course, in patients we found decreae of total cholesterol from 4,4±1,4 to 3,9±1,1 (р=0,02); low density lipoproteides level from 2,6±1,1 to 2,1±0,7 (р=0,002); significant increase of high density lipoproteides from 0,9±0,3 to 1,2±0,4 min (р<0,001) and left ventricle ejection fraction from 55±8,3% to 60,6±8,2% (p<0,001). Significant decrease of the resting heartrate (HR) from 72,9±10,3 bpm to 67,9±6 bpm (р=0,04); mean time of the HR recovery from 4,1±1,2 min to 3,8±1 min (р=0,03) and blood pressure from 4,2±1,1 min to 3,8±1 min (р=0,013) after exercise testing; significant increase of exercise tolerance to physical exertion from 4,0±1,5 МЕТ to 5,0±1,7 МЕТ (p<0,001) and time of test from 5,0±1,9 min to 6,7±2 min (p<0,001).Concusion. 12-week program of cardiorehabilitation leads to significant normalization of carbohydrate and lipid metabolisms, helps to increase exercise tolerance and significantly recovers the hemodynamical parameters of circulation.

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