mBio (Oct 2021)

Lipidation of Class IV CdiA Effector Proteins Promotes Target Cell Recognition during Contact-Dependent Growth Inhibition

  • Tiffany M. Halvorsen,
  • Fernando Garza-Sánchez,
  • Zachary C. Ruhe,
  • Nicholas L. Bartelli,
  • Nicole A. Chan,
  • Josephine Y. Nguyen,
  • David A. Low,
  • Christopher S. Hayes

Journal volume & issue
Vol. 12, no. 5


Read online

Contact-dependent growth inhibition (CDI) is a common form of interbacterial competition in which cells use CdiA effectors to deliver toxic proteins into their neighbors. CdiA recognizes target bacteria through specific receptor molecules on the cell surface.