Communications Biology (Sep 2021)

Burkholderia PglL enzymes are Serine preferring oligosaccharyltransferases which target conserved proteins across the Burkholderia genus

  • Andrew J. Hayes,
  • Jessica M. Lewis,
  • Mark R. Davies,
  • Nichollas E. Scott

DOI
https://doi.org/10.1038/s42003-021-02588-y
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 12

Abstract

Read online

Hayes et al provide a glycosylation site focused analysis of the glycoproteome of two widely utilized B. cenocepacia strains, K56-2 and H111. This team demonstrates that within these glycoproteomes Serine is the sole residue targeted for protein glycosylation and that glycoproteins/glycosylation sites are highly conserved across B. cenocepacia isolates.