Autonomous regulation of cardiovascular system in healthy people and patients with Stage I arterial hypertension

Abstract

The study included 25 men (mean age 29,24±0,76 years) with Stage I arterial hypertension (AH I) and 25 healthy male controls (mean age 30,27±0,59 years). Both groups underwent 24-hour blood pressure monitoring (BPM), echocardiography (EchoCG) with Doppler ultrasound, heart rate variability (HRV) assessment and measurement of serum cholesterol and its fractions. Analysing correlations between autonomous regulation parameters, cholesterol and cholesterol fractions, and myocardial structure and function, it was observed that in AH I patients, both the number and strength of correlations were greater than in healthy controls. It could point to greater rigidity of neuro-humoral cardiovascular regulation in AH I patients, comparing to healthy individuals.

Keywords

• arterial hypertension
• heart rate variability
• neuro-humoral regulation
• young men