Early Life Trauma Predicts Affective Phenomenology and the Effects are Partly Mediated by Staging Coupled with Lowered Lipid-Associated Antioxidant Defences

Maes Michael; Congio Ana; Moraes Juliana Brum; Bonifacio Kamila Landucci; Barbosa Decio Sabbatini; Vargas Heber Odebrecht; Morris Gerwyn; Puri Basant K.; Michelin Ana Paula; Nunes Sandra Odebrecht Vargas

doi:10.1515/bmc-2018-0010

Biomolecular Concepts (Nov 2018)

Early Life Trauma Predicts Affective Phenomenology and the Effects are Partly Mediated by Staging Coupled with Lowered Lipid-Associated Antioxidant Defences

Maes Michael,
Congio Ana,
Moraes Juliana Brum,
Bonifacio Kamila Landucci,
Barbosa Decio Sabbatini,
Vargas Heber Odebrecht,
Morris Gerwyn,
Puri Basant K.,
Michelin Ana Paula,
Nunes Sandra Odebrecht Vargas

Affiliations

Maes Michael: Health Sciences Graduate Program, Health Sciences Center, State University of Londrina, Av. Robert Koch 60; 86035-380, Londrina, PR, Brazil
Congio Ana: Health Sciences Graduate Program, Health Sciences Center, State University of Londrina, Av. Robert Koch 60; 86035-380, Londrina, PR, Brazil
Moraes Juliana Brum: Health Sciences Graduate Program, Health Sciences Center, State University of Londrina, Av. Robert Koch 60; 86035-380, Londrina, PR, Brazil
Bonifacio Kamila Landucci: Health Sciences Graduate Program, Health Sciences Center, State University of Londrina, Av. Robert Koch 60; 86035-380, Londrina, PR, Brazil
Barbosa Decio Sabbatini: Health Sciences Graduate Program, Health Sciences Center, State University of Londrina, Av. Robert Koch 60; 86035-380, Londrina, PR, Brazil
Vargas Heber Odebrecht: Health Sciences Graduate Program, Health Sciences Center, State University of Londrina, Av. Robert Koch 60; 86035-380, Londrina, PR, Brazil
Morris Gerwyn: IMPACT Strategic Research Centre, Deakin University, Geelong, Vic, Australia
Puri Basant K.: Department of Medicine, Imperial College London, London, UK
Michelin Ana Paula: Health Sciences Graduate Program, Health Sciences Center, State University of Londrina, Av. Robert Koch 60; 86035-380, Londrina, PR, Brazil
Nunes Sandra Odebrecht Vargas: Health Sciences Graduate Program, Health Sciences Center, State University of Londrina, Av. Robert Koch 60; 86035-380, Londrina, PR, Brazil

DOI: https://doi.org/10.1515/bmc-2018-0010
Journal volume & issue: Vol. 9, no. 1
pp. 115 – 130

Abstract

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Early life trauma (ELT) may drive mood disorder phenomenology, nitro-oxidative pathways and impairments in semantic memory. There are no data regarding the impact of ELT on affective phenomenology and whether these pathways are mediated by staging or lowered lipid-associated antioxidant defences.

Published in Biomolecular Concepts

ISSN: 1868-5021 (Print); 1868-503X (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Science: Biology (General)
Website: https://www.degruyter.com/view/j/bmc

About the journal

Abstract

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