Silver-based drug effect on the body of calves with diarrhea

Abstract

Diarrhea of newborn calves is a globally common disease that causes significant damage to livestock. Economic losses from diarrhea in young cattle are directly related to the cost of long-term treatment of animals and their mortality, as well as the projected decrease in productivity, which negatively affects the efficiency of maintaining the entire herd. Currently, it is an established fact that diarrhea of newborn calves has a polyethological nature, which has an interaction in pathogenesis between the calf’s body, enteropathogens and the technology of keeping animals. For the treatment of calves with diarrhea caused by enteropathogenic Escherichia coli, many methods and schemes using various antibiotics have been proposed. The need for fast and efficient treatment for acute diarrhea of calves in many cases leads to an empirical selection of the drug without taking into account the spectrum of its activity. This approach leads to the appearance and rapid spread of antibiotic resistant strains of microorganisms and as a result reduces the effectiveness of veterinary measures. The article presents the results of a study of the effect of a new complex drug containing stabilized silver particles, an immunostimulator and an antioxidant on the body of calves with diarrhea, as an alternative to the antibiotics. Studies were conducted on calves of the first week of life with a diagnosis of diarrhea, with enteropathogenic Escherichia coli confirmation.