Individualizatsiya terapii tsentral'nogo nesakharnogo diabeta: klinicheskiy sluchay primeneniya preparata «Presayneks»

Abstract

Central diabetes insipidus (CDI) - a severe disease with disturbance of arginine vasopressin secretion, with excretion of large amounts of hypotonic urine, which leads to dehydration and thirst. Desmopressin, a synthetic analog of arginine vasopressin, is used to compensate a water-electrolyte balance in patients with CDI is available in forms of intranasal spray and tablets. Herein we present a clinical case of a patient with longstanding CDI due to Langerhans cell hystiocytosis in childhood who received different medications for treatment of CDI symptoms that demonstrates variable efficiency and tolerance of these drugs.

Keywords

• diabetes insipidus
• vasopressin
• desmopressin
• presinex
• minirin
• hystiocytosis