Journal of Cardiovascular Development and Disease (Nov 2023)

The VEST External Support for Saphenous Vein Grafts in Coronary Surgery: A Review of Randomized Clinical Trials

  • Giovanni Jr. Soletti,
  • Michele Dell’Aquila,
  • Lamia Harik,
  • Gianmarco Cancelli,
  • Talal Alzghari,
  • Roberto Perezgrovas-Olaria,
  • Arnaldo Dimagli,
  • Kevin R. An,
  • Jordan Leith,
  • Camilla Sofia Rossi,
  • Christopher F. Barile,
  • Michelle Demetres,
  • Christopher Lau,
  • Leonard N. Girardi,
  • Mario Gaudino

DOI
https://doi.org/10.3390/jcdd10110453
Journal volume & issue
Vol. 10, no. 11
p. 453

Abstract

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Saphenous vein grafts (SVGs) are the most frequently used conduits in coronary artery bypass grafting (CABG), but their higher rate of occlusion compared to arterial conduits remains a concern. Previous studies have shown that SVG failure is mainly driven by intimal hyperplasia, an adaptative response to higher pressures of the arterial circulation. The VESTTM device (Vascular Graft Solutions, Tel Aviv, Israel), an external support designed to mitigate intimal hyperplasia in SVGs, has been tested in few clinical trials (RCTs). Herein, we descriptively evaluated the randomized evidence on the VEST device.

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