Nature Communications (Aug 2018)

Molecular insights into Vibrio cholerae’s intra-amoebal host-pathogen interactions

  • Charles Van der Henst,
  • Audrey Sophie Vanhove,
  • Natália Carolina Drebes Dörr,
  • Sandrine Stutzmann,
  • Candice Stoudmann,
  • Stéphanie Clerc,
  • Tiziana Scrignari,
  • Catherine Maclachlan,
  • Graham Knott,
  • Melanie Blokesch

DOI
https://doi.org/10.1038/s41467-018-05976-x
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 13

Abstract

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The causative agent of cholera, Vibrio cholerae, is commonly found in aquatic habitats, where it must defend itself against predatory protists such as amoebae. Here, Van der Henst et al. analyze the molecular mechanisms by which V. cholerae thrives within, and ultimately escapes from, aquatic amoebae.