mBio
(Jun 2021)
DegP Initiates Regulated Processing of Filamentous Hemagglutinin in Bordetella bronchiseptica
Richard M. Johnson,
Zachary M. Nash,
Margaret R. Dedloff,
John C. Shook,
Peggy A. Cotter
Affiliations
Richard M. Johnson
ORCiD Department of Microbiology and Immunology, School of Medicine, University of North Carolina—Chapel Hill, Chapel Hill, North Carolina, USA
Zachary M. Nash
Department of Microbiology and Immunology, School of Medicine, University of North Carolina—Chapel Hill, Chapel Hill, North Carolina, USA
Margaret R. Dedloff
Department of Microbiology and Immunology, School of Medicine, University of North Carolina—Chapel Hill, Chapel Hill, North Carolina, USA
John C. Shook
Department of Microbiology and Immunology, School of Medicine, University of North Carolina—Chapel Hill, Chapel Hill, North Carolina, USA
Peggy A. Cotter
ORCiD Department of Microbiology and Immunology, School of Medicine, University of North Carolina—Chapel Hill, Chapel Hill, North Carolina, USA
DOI
https://doi.org/10.1128/mBio.01465-21
Journal volume & issue
Vol. 12,
no. 3
Abstract
Read online
Two-partner secretion (TPS) systems are broadly distributed among Gram-negative bacteria and play important roles in bacterial pathogenesis. FhaB-FhaC is the prototypical member of the TPS family and we here identified the protease that initiates a processing cascade that controls FhaB function.
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