Frontiers in Medicine (Nov 2021)

Rapid Progression of Angioimmunoblastic T Cell Lymphoma Following BNT162b2 mRNA Vaccine Booster Shot: A Case Report

  • Serge Goldman,
  • Dominique Bron,
  • Thomas Tousseyn,
  • Irina Vierasu,
  • Laurent Dewispelaere,
  • Pierre Heimann,
  • Elie Cogan,
  • Michel Goldman

DOI
https://doi.org/10.3389/fmed.2021.798095
Journal volume & issue
Vol. 8

Abstract

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Since nucleoside-modified mRNA vaccines strongly activate T follicular helper cells, it is important to explore the possible impact of approved SARS-CoV-2 mRNA vaccines on neoplasms affecting this cell type. Herein, we report and discuss unexpected rapid progression of lymphomatous lesions after administration of a BNT162b2 mRNA vaccine booster in a man recently diagnosed with AITL.

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