E3S Web of Conferences (Jan 2021)

Xenobiotics: a Threat to the Health of Living Organisms

  • Kucherenko Svetlana V.,
  • Ovcharenko Alla M.,
  • Pushenko Sergey L.

DOI
https://doi.org/10.1051/e3sconf/202128503006
Journal volume & issue
Vol. 285
p. 03006

Abstract

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The article summarizes and analyzes the main impacts of various xenobiotics or their groups on the human body and the consequences of such exposure. The study suggests the refinements to the generally accepted classification of xenobiotics’ origins. The paper also describes the molecular mechanism of foreign substances biotransformation in a human body. The metabolism of xenobiotics differs due to their forms and types’ varieties. The factors of influence on chemicals’ metabolism are also of great importance. Individual features of the metabolism may be associated with genetic differences in the activity of metabolic enzymes. The research results further the comprehension of the exposure pathways and health impacts of the xenobiotics and their metabolites.