Assessment of the operative memory capacity based on endogenous evoked potentials (P300 method) without neuropsychological testing

Abstract

We analyzed the dependence of the operative memory (OP) capacityon P300 parameters in healthy individuals and patientswith a varying degree of memory impairments. Our findingsdemonstrated a strong correlation between the OP capacity andthe P300 latent period. On this basis, we provided a atisfactoryquantitative description of OP using the P300 latent period thatwas comparable to neuropsychological testing in most individualsand patients. Thus, the P300 method provides a quantitativemeasure of OP, which is particularly important when neuropsychologicaltesting is not possible for some reasons, e.g., aphasia,unresponsive state, etc.

Keywords

• cognitive evoked potentials
• p300
• operative memory
• neuropsychological testing
• regression line