Nature Communications (Mar 2021)

A multiplexed, automated evolution pipeline enables scalable discovery and characterization of biosensors

  • Brent Townshend,
  • Joy S. Xiang,
  • Gabriel Manzanarez,
  • Eric J. Hayden,
  • Christina D. Smolke

DOI
https://doi.org/10.1038/s41467-021-21716-0
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 15

Abstract

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Biosensors are key to engineered biological systems. Here the authors demonstrate rapid de novo in vitro evolution of RNA biosensors of small molecules in a fully automated system.