Indian Journal of Ophthalmology (Jan 2014)
Influence of multiple sclerosis, age and degree of disability, in the position of the contrast sensitivity curve peak
- A F Nunes,
- P M L Monteiro,
- M Vaz Pato
Affiliations
- A F Nunes
- P M L Monteiro
- M Vaz Pato
- DOI
- https://doi.org/10.4103/0301-4738.116485
- Journal volume & issue
-
Vol. 62,
no. 2
pp. 180 – 185
Abstract
Context: Contrast sensitivity (CS) function is one of the most important tests available for evaluating visual impairment. Multiple sclerosis (MS) can produce highly selective losses in visual function and psychophysical studies have demonstrated CS deficits for some spatial frequencies. Aims: This work studies the differences in CS between a group of controls and a group of MS patients, focusing on the location of the maximum sensitivity peak, shape of the curve, and determination of the most affected spatial frequencies. Materials and Methods: Using a sinusoidal stimulus the authors assessed CS function in 28 subjects with definitive relapsing remitting MS, and in 50 controls with acuities of 20/25 or better. The peaks of the CS curves were studied by fitting third degree polynomials to individual sets of data. Results: Compared with the control group, the CS function curve for MS subjects showed more deficits in extreme points (low- and high-spatial frequencies). Our results display significant CS losses, at the high-frequencies band level, in the beginning of the disease. When the disease progresses and the disabilities appear, there are greater losses at the low-frequencies band level. In average, the CS curve peaks for the MS group were shifted in relation to the control group. Conclusions: CS losses in the MS group suggest an association with ageing and disability level in the expanded disability status scale. The position of the CS function peak is influenced by MS, age, and degree of disability.
Keywords
- Blindness
- cataract
- eye lens
- risk factors
- treatment of cataract
- Low vision care
- multiple disabilities and visual impairment
- reading performance
- Accommodation
- presbyopia
- supraciliary segment implants
- Amblyopia
- citicoline
- patching
- Corneal endothelium
- human corneal endothelial precursor cells
- in vitro expansion
- sphere forming assay
- thermo-reversible gelation polymer
- transportation
- Endophthalmitis
- explantation
- fungal
- intraocular lens
- postoperative
- recurrent
- Colour perception
- learning disabilities
- school children
- stereo acuity
- testability
- visual acuity
- Contracted socket
- dermis fat graft
- porous orbital implant
- reconstruction
- Glucose
- in vitro anticataract
- lens
- Moringa oliefera
- ′BARC I-125 Ocu-Prosta seeds′
- choroidal melanoma
- ciliary body melanoma
- Episcleral plaque brachytherapy
- retinal angioma
- retinoblastoma
- vasoproliferative tumor
- Congenital glaucoma
- gonioscopy
- Retcam
- Acoustic features
- A-scan
- B-scan
- choroidal mass
- ultrasound biomicroscopy
- Cataract surgery
- education
- informed consent
- multimedia
- rural health
- Lagophthalmos
- silicone sling
- temporalis muscle
- Contrast sensitivity function
- disability
- function peak
- multiple sclerosis
- spatial frequency