Bedaquiline and Linezolid for Extensively Drug-Resistant Tuberculosis in Pregnant Woman

Abstract

A woman with extremely drug-resistant tuberculosis treated with a drug regimen including linezolid and bedaquiline during her last 3 weeks of pregnancy gave birth to a child without abnormalities. No fetal toxicities were noted by 2 years after delivery. This drug combination might be safe during the late third trimester of pregnancy.

Keywords

• MDR-TB
• pregnancy
• linezolid
• bedaquiline
• Mycobacterium tuberculosis
• multidrug-resistant tuberculosis