Prognosis Analysis of Non-small Cell Lung Cancer with Diameter over 7.0 cm Based on SEER Database

FENG Tingting; CHEN Zhongzhong; YAN Wenjin; WANG Yuxiu; ZHANG Jun; XU Xingxiang; CHEN Yong; YANG Junjun; MIN Lingfeng

doi:10.3971/j.issn.1000-8578.2021.19.1587

Zhongliu Fangzhi Yanjiu (Jan 2021)

Prognosis Analysis of Non-small Cell Lung Cancer with Diameter over 7.0 cm Based on SEER Database

FENG Tingting,
CHEN Zhongzhong,
YAN Wenjin,
WANG Yuxiu,
ZHANG Jun,
XU Xingxiang,
CHEN Yong,
YANG Junjun,
MIN Lingfeng

Affiliations

FENG Tingting: Department of Respiratory and Critical Care Medicine, Northern Jiangsu People's Hospital, The First Clinical College of Dalian Medical University, Clinical Medical College of Yangzhou University, Yangzhou 225001, China
CHEN Zhongzhong: Department of Respiratory and Critical Care Medicine, Northern Jiangsu People's Hospital, The First Clinical College of Dalian Medical University, Clinical Medical College of Yangzhou University, Yangzhou 225001, China
YAN Wenjin: Department of Respiratory and Critical Care Medicine, Northern Jiangsu People's Hospital, The First Clinical College of Dalian Medical University, Clinical Medical College of Yangzhou University, Yangzhou 225001, China
WANG Yuxiu: Department of Respiratory and Critical Care Medicine, Northern Jiangsu People's Hospital, The First Clinical College of Dalian Medical University, Clinical Medical College of Yangzhou University, Yangzhou 225001, China
ZHANG Jun: Department of Respiratory and Critical Care Medicine, Northern Jiangsu People's Hospital, The First Clinical College of Dalian Medical University, Clinical Medical College of Yangzhou University, Yangzhou 225001, China
XU Xingxiang: Department of Respiratory and Critical Care Medicine, Northern Jiangsu People's Hospital, The First Clinical College of Dalian Medical University, Clinical Medical College of Yangzhou University, Yangzhou 225001, China
CHEN Yong: Department of Respiratory and Critical Care Medicine, Northern Jiangsu People's Hospital, The First Clinical College of Dalian Medical University, Clinical Medical College of Yangzhou University, Yangzhou 225001, China
YANG Junjun: Department of Respiratory and Critical Care Medicine, Northern Jiangsu People's Hospital, The First Clinical College of Dalian Medical University, Clinical Medical College of Yangzhou University, Yangzhou 225001, China
MIN Lingfeng: Department of Respiratory and Critical Care Medicine, Northern Jiangsu People's Hospital, The First Clinical College of Dalian Medical University, Clinical Medical College of Yangzhou University, Yangzhou 225001, China

DOI: https://doi.org/10.3971/j.issn.1000-8578.2021.19.1587
Journal volume & issue: Vol. 48, no. 1
pp. 49 – 54

Abstract

Read online

Objective To analyze the mortality risk and evaluate the curative effects of surgery and non-surgery on NSCLC with diameter > 7.0 cm. Methods We collected the data of NSCLC patients with diameter > 7.0 cm from 2010 to 2015 from the SEER database. The 1, 2, 3-year survival rates were analyzed by life table method. Overall survival curve was estimated by Kaplan-Meier method. Univariate and multivariate Cox regression models were used to analyze the independent prognostic factors. Results The 1, 2, 3-year survival rates were 51.8%, 33.0% and 25.0%, respectively. In univariate and multivariate analyses, tumor size, N stage and treatment were the independent prognostic factors (P 7.0 cm. And for stage N2 NSCLC patients with diameter 7.0-9.0 cm, surgical treatment has advantages in improving the prognosis. Surgical and non-surgical patients with tumor diameter ≥9.0 cm or lymph node N3 stage have no statistically significant differences in prognosis. In addition, palliative treatment does not improve the prognosis of patients.

Published in Zhongliu Fangzhi Yanjiu

ISSN: 1000-8578 (Print)
Publisher: Magazine House of Cancer Research on Prevention and Treatment
Country of publisher: China
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: http://www.zlfzyj.com

About the journal

Abstract

Keywords