Nature Communications (Mar 2017)
Lnc-mg is a long non-coding RNA that promotes myogenesis
- Mu Zhu,
- Jiafan Liu,
- Jia Xiao,
- Li Yang,
- Mingxiang Cai,
- Hongyu Shen,
- Xiaojia Chen,
- Yi Ma,
- Sumin Hu,
- Zuolin Wang,
- An Hong,
- Yingxian Li,
- Yao Sun,
- Xiaogang Wang
Affiliations
- Mu Zhu
- Department of Cell Biology and Institute of Biomedicine, Guangdong Provincial Key Laboratory of Bioengineering Medicine & National Engineering Research Center of Genetic Medicine, Jinan University
- Jiafan Liu
- Department of Cell Biology and Institute of Biomedicine, Guangdong Provincial Key Laboratory of Bioengineering Medicine & National Engineering Research Center of Genetic Medicine, Jinan University
- Jia Xiao
- State Key Discipline of Infectious Diseases, Shenzhen Third People’s Hospital
- Li Yang
- Department of Cell Biology and Institute of Biomedicine, Guangdong Provincial Key Laboratory of Bioengineering Medicine & National Engineering Research Center of Genetic Medicine, Jinan University
- Mingxiang Cai
- Shanghai Engineering Research Center of Tooth Restoration and Regeneration, School and Hospital of Stomatology, Tongji University
- Hongyu Shen
- Department of Cell Biology and Institute of Biomedicine, Guangdong Provincial Key Laboratory of Bioengineering Medicine & National Engineering Research Center of Genetic Medicine, Jinan University
- Xiaojia Chen
- Department of Cell Biology and Institute of Biomedicine, Guangdong Provincial Key Laboratory of Bioengineering Medicine & National Engineering Research Center of Genetic Medicine, Jinan University
- Yi Ma
- Department of Cell Biology and Institute of Biomedicine, Guangdong Provincial Key Laboratory of Bioengineering Medicine & National Engineering Research Center of Genetic Medicine, Jinan University
- Sumin Hu
- Preclinical Medical School, Beijing University of Chinese Medicine
- Zuolin Wang
- Shanghai Engineering Research Center of Tooth Restoration and Regeneration, School and Hospital of Stomatology, Tongji University
- An Hong
- Department of Cell Biology and Institute of Biomedicine, Guangdong Provincial Key Laboratory of Bioengineering Medicine & National Engineering Research Center of Genetic Medicine, Jinan University
- Yingxian Li
- State Key Laboratory of Space Medicine Fundamentals and Application, China Astronaut Research and Training Center
- Yao Sun
- Shanghai Engineering Research Center of Tooth Restoration and Regeneration, School and Hospital of Stomatology, Tongji University
- Xiaogang Wang
- Department of Cell Biology and Institute of Biomedicine, Guangdong Provincial Key Laboratory of Bioengineering Medicine & National Engineering Research Center of Genetic Medicine, Jinan University
- DOI
- https://doi.org/10.1038/ncomms14718
- Journal volume & issue
-
Vol. 8,
no. 1
pp. 1 – 11
Abstract
Long non-coding mRNAs play important roles in muscle development and regeneration. Here the authors identify a long non-coding mRNA that promotes myogenesis by sequestering miR-125b, leading to increased expression of insulin-like growth factor 2.
