Nature Communications (Nov 2022)

Small molecule-assisted assembly of multifunctional ceria nanozymes for synergistic treatment of atherosclerosis

  • Xiaoxue Fu,
  • Xiaojuan Yu,
  • Junhao Jiang,
  • Jiaxin Yang,
  • Lu Chen,
  • Zhangyou Yang,
  • Chao Yu

DOI
https://doi.org/10.1038/s41467-022-34248-y
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 14

Abstract

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Regulating reactive oxygen species and inflammation are important for treating atherosclerosis. Here, the authors create a cell membrane coated zoledronic acid ceria nanocomposite loaded with probucol for synergistic drug and scavenging nanozyme treatment of atherosclerosis demonstrating application in vivo.