PLoS ONE (Jan 2011)

The burden of common infectious disease syndromes at the clinic and household level from population-based surveillance in rural and urban Kenya.

  • Daniel R Feikin,
  • Beatrice Olack,
  • Godfrey M Bigogo,
  • Allan Audi,
  • Leonard Cosmas,
  • Barrack Aura,
  • Heather Burke,
  • M Kariuki Njenga,
  • John Williamson,
  • Robert F Breiman

DOI
https://doi.org/10.1371/journal.pone.0016085
Journal volume & issue
Vol. 6, no. 1
p. e16085

Abstract

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BackgroundCharacterizing infectious disease burden in Africa is important for prioritizing and targeting limited resources for curative and preventive services and monitoring the impact of interventions.MethodsFrom June 1, 2006 to May 31, 2008, we estimated rates of acute lower respiratory tract illness (ALRI), diarrhea and acute febrile illness (AFI) among >50,000 persons participating in population-based surveillance in impoverished, rural western Kenya (Asembo) and an informal settlement in Nairobi, Kenya (Kibera). Field workers visited households every two weeks, collecting recent illness information and performing limited exams. Participants could access free high-quality care in a designated referral clinic in each site. Incidence and longitudinal prevalence were calculated and compared using Poisson regression.ResultsINCIDENCE RATES RESULTING IN CLINIC VISITATION WERE THE FOLLOWING: ALRI--0.36 and 0.51 episodes per year for children ConclusionsIndividuals in poor Kenyan communities still suffer from a high burden of infectious diseases, which likely hampers their development. Urban slum and rural disease incidence and clinic utilization are sufficiently disparate in Africa to warrant data from both settings for estimating burden and focusing interventions.