Science & Research (Dec 2020)
MALFORMATION SYNDROME WITH TOTAL SITUS VISCERUM INVERSUS - CONTRAINDICATION FOR TISSUE DONATION
Abstract
We report a case of a 65-year-old woman who died with evidence of acute cardiac ischemia, despite receiving emergency medical care. The woman's body was promptly brought for autopsy to the Department of Forensic medicine and deontology, Medical University-Sofia, Bulgaria and placed in a forensic storage refrigerator. During the immediate external examination of the body and based on the results of the performed serological tests of the blood samples taken from the deceased, no medical data for contraindication for tissue donation were established. A conversation was made by the hospital donation coordinator with the daughter of the deceased for the possibility of tissue donation, where she gave her consent. In principle, to perform such a procedure in the Department of Forensic medicine and deontology, an autopsy should always be performed to exclude contraindications for tissue donation, and after the autopsy the standard documents required for this purpose are signed by the relatives. The autopsy of the deceased revealed the presence of a total situs viscerum inversus, as well as ischemic heart disease with multiple disseminated myocardiofibrosis, acute anterior septal myocardial infarction, two atrial septal defects and severe concentric hypertrophy of the heart. According to standard medical criteria, all types of genetic malformations are a contraindication for donation, which is why, in this case, the donation procedure was terminated.
