Asian Pacific Journal of Tropical Medicine (Jan 2021)

Extensively drug-resistant Salmonella typhi causing rib osteomyelitis: A case report

  • Sara Iqbal,
  • Humza Thobani,
  • Saulat Fatimi

DOI
https://doi.org/10.4103/1995-7645.315892
Journal volume & issue
Vol. 14, no. 5
pp. 231 – 233

Abstract

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Rationale: Salmonella (S.) typhi is a rare cause of osteomyelitis in immunocompetent adults. Extensive drug resistance (XDR) may lead to more complicated cases of S. typhi osteomyelitis. Patient concern: A 55-year-old female presented with a persistent low-grade fever and a swelling on her lower left chest with a sinus discharging purulent fluid for the past 8 months. Her symptoms had been unresponsive to previous anti-microbial therapy. Diagnosis: Rib osteomyelitis caused by XDR S. typhi. Interventions: Surgical wound debridement, left 7th-9th rib resection and intravenous IV meropenem were done. Outcome: Fever resolved and left-sided swelling resected without recurrence. Lessons: The prevalence of XDR S. typhi is growing in South Asia and should be considered as the differential diagnosis of chronic osteomyelitis.

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