Inhibition of multi-drug resistant microbial pathogens using an eco-friendly root extract of Furcraea foetida mediated silver nanoparticles

R. Sitrarasi; V. Uma Maheshwari Nallal; M. Razia; Woo Jin Chung; Jaehong Shim; Murugesan Chandrasekaran; Yheni Dwiningsih; Rabab Ahmed Rasheed; Jawaher Alkahtani; Mohamed S. Elshikh; Debnath Ovi; Balasubramani Ravindran

Journal of King Saud University: Science (Feb 2022)

Inhibition of multi-drug resistant microbial pathogens using an eco-friendly root extract of Furcraea foetida mediated silver nanoparticles

R. Sitrarasi,
V. Uma Maheshwari Nallal,
M. Razia,
Woo Jin Chung,
Jaehong Shim,
Murugesan Chandrasekaran,
Yheni Dwiningsih,
Rabab Ahmed Rasheed,
Jawaher Alkahtani,
Mohamed S. Elshikh,
Debnath Ovi,
Balasubramani Ravindran

Affiliations

R. Sitrarasi: Department of Biotechnology, Mother Teresa Women’s University, Kodaikanal 624101, India
V. Uma Maheshwari Nallal: Department of Biotechnology, Mother Teresa Women’s University, Kodaikanal 624101, India
M. Razia: Department of Biotechnology, Mother Teresa Women’s University, Kodaikanal 624101, India; Corresponding authors.
Woo Jin Chung: Department of Environmental Energy and Engineering, Kyonggi University Youngtong-Gu, Suwon, Gyeonggi-Do 16227, South Korea
Jaehong Shim: Soil and Fertilizer Management Division, Rural Development Administration, National Institute of Agricultural Science, Wanju-gun, South Korea
Murugesan Chandrasekaran: Department of Food Science and Biotechnology, Sejong University, Gwangjin-gu, Seoul 05006, South Korea; Corresponding authors.
Yheni Dwiningsih: Department of Crop, Soil and Environmental Sciences, University of Arkansas, Fayetteville, AR, USA
Rabab Ahmed Rasheed: Histology & Cell Biology Department, Faculty of Medicine, King Salman International University, South Sinai, Egypt
Jawaher Alkahtani: Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia
Mohamed S. Elshikh: Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia
Debnath Ovi: Department of Environmental Energy and Engineering, Kyonggi University Youngtong-Gu, Suwon, Gyeonggi-Do 16227, South Korea; Corresponding authors.
Balasubramani Ravindran: Department of Environmental Energy and Engineering, Kyonggi University Youngtong-Gu, Suwon, Gyeonggi-Do 16227, South Korea

Journal volume & issue: Vol. 34, no. 2
p. 101794

Abstract

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Objectives: Advancement in the biological process of nanoparticles synthesis is an important area of nanotechnology. The aim of this research is to utilize the root extract of Furcraea foetida as reduction and stabilization agents to biosynthesize. Silver nanoparticles (AgNPs) from AgNO3 via a simple green method. Methods: By utilizing UV–VIS spectroscopy, FTIR, XRD, Zeta potential, and HR-TEM techniques, the nanoparticles have been characterized. The anti-Candida properties of AgNPs were tested using the well-diffusion method in agar plates against five Candida species. Results: With an average diameter of 15 nm, the produced AgNPs are spherical. They were found to be stable and non-aggregated. The synthesized nanoparticles were active against all the tested organisms and showed better efficacy compared to Amphotericin B in most cases. The highest level of inhibition was found against C. albicans at 100 µg concentration. Conclusion: The results prove that F. foetida is a very good bioreductant and can be used for one-pot synthesis of stable AgNPs with good anti-Candida activity.

Published in Journal of King Saud University: Science

ISSN: 1018-3647 (Print)
Publisher: Elsevier
Country of publisher: Saudi Arabia
LCC subjects: Science: Science (General)
Website: http://www.journals.elsevier.com/journal-of-king-saud-university-science/

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