Relationships between structure, in vivo function and long-range axonal target of cortical pyramidal tract neurons

Abstract

The major output cell type of the neocortex – pyramidal tract neurons (PTs) – send axonal projections to various subcortical areas. Here the authors combined in vivo recordings, retrograde tracings, and reconstructions of PTs in rat somatosensory cortex to show that PT structure and activity can predict specific subcortical targets.