A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory

Abstract

The mammalian hippocampal formation plays a key role in several higher brain functions. Here, the authors show that excitatory neurons in layer 6b of the mouse EC project to all sub-regions comprising the hippocampal formation and receive input from the CA1, thalamus and claustrum.