Impact of Platelet Count in Retinopathy of Prematurity

Abstract

Objectives:The aim of the study was to investigate the risk factors for retinopathy of prematurity (ROP), including platelet count.Materials and Methods:This retrospective study analyzed 137 infants in 3 subgroups: no ROP; mild ROP, and severe ROP requiring laser treatment (type 1 ROP). A retrospective review of records was performed and statistical analysis of possible risk factors for ROP including platelet count was evaluated by using logistic regression.Results:Birth weight (BW), gestational age (GA), and low platelet count in the first week after birth were significant risk factors for developing ROP (p=0.038, 0.02, and 0.004, respectively). BW, GA, ventilation, and lower platelet count were associated with progression to type 1 ROP (p=0.004; 0.027, and 0.021, respectively).Conclusion:Lower platelet count in the first week after birth is a risk factor for ROP development in addition to the previously established factors of ventilation need, low BW, and low GA.

Keywords

• birth weight
• gestational age
• retinopathy of prematurity
• risk factors
• platelet