Association of HIF-1α and NDRG2 expression with EMT in gastric cancer tissues

Wang Ren-Xiang; Ou Xia-Wan; Kang Ma-Fei; Zhou Zu-Ping

doi:10.1515/biol-2019-0025

Open Life Sciences (Jul 2019)

Association of HIF-1α and NDRG2 expression with EMT in gastric cancer tissues

Wang Ren-Xiang,
Ou Xia-Wan,
Kang Ma-Fei,
Zhou Zu-Ping

Affiliations

Wang Ren-Xiang: Clinical medical school of Guilin Medical College, Guilin, Guangxi, 541001, China
Ou Xia-Wan: Clinical medical school of Guilin Medical College, Guilin, Guangxi, 541001, China
Kang Ma-Fei: Department of Medical Oncology, The Affiliated Hospital of Guilin Medical College, Guilin, Guangxi, 541001, China
Zhou Zu-Ping: Guangxi Normal University, College of Life Science; Stem Cells and Medical Biological Technology Key Laboratory of Guangxi Colleges and Universities, Guilin, Guangxi, 541004, China

DOI: https://doi.org/10.1515/biol-2019-0025
Journal volume & issue: Vol. 14, no. 1
pp. 217 – 223

Abstract

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This study aims to investigate the differences in the expression of hypoxia-inducible factor-1α (HIF-1α), N-myc downstream-regulated gene 2 (NDRG2) and epithelial mesenchymal transition (EMT)-related proteins in normal gastric tissues, gastric cancer tissues and lymph node metastasis.

Published in Open Life Sciences

ISSN: 2391-5412 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Science: Biology (General)
Website: http://www.degruyter.com/view/j/biol

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Abstract

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