An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity

• Qi Zhou,
• Pablo Catalán,
• Helen Bell,
• Patrick Baumann,
• Rebekah Cooke,
• Rhodri Evans,
• Jianhua Yang,
• Zhen Zhang,
• Davide Zappalà,
• Ye Zhang,
• George Michael Blackburn,
• Yuan He,
• Yi Jin

Affiliations

Qi Zhou

Key Laboratory of Synthetic and Natural Functional Molecule, College of Chemistry and Materials Science, Northwest University, Xi’an, P. R. China

Pablo Catalán

Grupo Interdisciplinar de Sistemas Complejos, Departamento de Matemáticas, Universidad Carlos III de Madrid, Leganés, Spain

Helen Bell

School of Chemistry, Cardiff University, Cardiff, United Kingdom

Patrick Baumann

School of Chemistry, Cardiff University, Cardiff, United Kingdom

Rebekah Cooke

School of Chemistry, Cardiff University, Cardiff, United Kingdom

Rhodri Evans

School of Chemistry, Cardiff University, Cardiff, United Kingdom

Jianhua Yang

Key Laboratory of Synthetic and Natural Functional Molecule, College of Chemistry and Materials Science, Northwest University, Xi’an, P. R. China

Zhen Zhang

Key Laboratory of Synthetic and Natural Functional Molecule, College of Chemistry and Materials Science, Northwest University, Xi’an, P. R. China

Davide Zappalà

School of Chemistry, Cardiff University, Cardiff, United Kingdom

Ye Zhang

Key Laboratory of Synthetic and Natural Functional Molecule, College of Chemistry and Materials Science, Northwest University, Xi’an, P. R. China

George Michael Blackburn

School of Biosciences, University of Sheffield, Sheffield, United Kingdom

Yuan He

Key Laboratory of Synthetic and Natural Functional Molecule, College of Chemistry and Materials Science, Northwest University, Xi’an, P. R. China

Yi Jin

School of Chemistry, Cardiff University, Cardiff, United Kingdom