Cognition and comorbidity in postmenopausal women

Abstract

Objective: to assess frequency and clinical significance of cognitive function impairment in postmenopausal woman. Methods: A cross-sectional study included 462 women under the age of 65. Arterial hypertension, carbohydrate metabolism impairment, chronic heart failure, coronary heart disease frequency were registered. Mini Mental State Examination was used to assess cognitive function. Results: mild cognitive function impairment was found in 223 (48%) postmenopausal women, 28 cases (6%) of dementia were registered. Mild cognitive impairment was associated with arterial hypertension (OR 1.74; 95% CI 1.16 – 2.64), chronic heart failure (OR 1.70; 1.16 – 2.49), dementia was associated with coronary heart disease (3.49; 1.54>7.89). Conclusion: cognitive impairment is frequent in postmenopausal women and associated with arterial hypertension, chromic heart failure and coronary heart disease.