Respirology Case Reports (Feb 2024)

Pulmonary adenoid cystic carcinoma ‐ a spectrum of disease: two case reports

  • Margaret Gleeson,
  • Megan Finan,
  • Karen Redmond

DOI
https://doi.org/10.1002/rcr2.1230
Journal volume & issue
Vol. 12, no. 2
pp. n/a – n/a

Abstract

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Abstract Adenoid cystic carcinoma (ACC) is a rare form of adenocarcinoma that usually begins in the oral cavity, with most cases arising from the salivary glands. Owing to its low incidence, the precise clinical and pathological features, including therapeutic strategy and survival data have not been conclusively reported. ACCs are typically characterized by slow growth, perineural invasion with local and often late recurrence after initial diagnosis. However, some cases demonstrate unusual aggressive biologic behaviour. Herein we describe our experience of two patients with a diagnosis of ACC. These cases highlight the spectrum of the disease with individualized treatment strategies.

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