Distance-Based Paper Device Combined with Headspace Extraction for Determination of Cyanide
Papichaya Khatha,
Thanyarat Phutthaphongloet,
Phenphitcha Timpa,
Benjawan Ninwong,
Kamolwich Income,
Nalin Ratnarathorn,
Wijitar Dungchai
Affiliations
Papichaya Khatha
Organic Synthesis, Electrochemistry & Natural Product Research Unit, Department of Chemistry, Faculty of Science, King Mongkut’s University of Technology Thonburi, Prachautid Road, Thungkru, Bangkok 10140, Thailand
Thanyarat Phutthaphongloet
Organic Synthesis, Electrochemistry & Natural Product Research Unit, Department of Chemistry, Faculty of Science, King Mongkut’s University of Technology Thonburi, Prachautid Road, Thungkru, Bangkok 10140, Thailand
Phenphitcha Timpa
Organic Synthesis, Electrochemistry & Natural Product Research Unit, Department of Chemistry, Faculty of Science, King Mongkut’s University of Technology Thonburi, Prachautid Road, Thungkru, Bangkok 10140, Thailand
Benjawan Ninwong
Organic Synthesis, Electrochemistry & Natural Product Research Unit, Department of Chemistry, Faculty of Science, King Mongkut’s University of Technology Thonburi, Prachautid Road, Thungkru, Bangkok 10140, Thailand
Kamolwich Income
Organic Synthesis, Electrochemistry & Natural Product Research Unit, Department of Chemistry, Faculty of Science, King Mongkut’s University of Technology Thonburi, Prachautid Road, Thungkru, Bangkok 10140, Thailand
Nalin Ratnarathorn
Organic Synthesis, Electrochemistry & Natural Product Research Unit, Department of Chemistry, Faculty of Science, King Mongkut’s University of Technology Thonburi, Prachautid Road, Thungkru, Bangkok 10140, Thailand
Wijitar Dungchai
Organic Synthesis, Electrochemistry & Natural Product Research Unit, Department of Chemistry, Faculty of Science, King Mongkut’s University of Technology Thonburi, Prachautid Road, Thungkru, Bangkok 10140, Thailand
We report for the first time a distance-based paper device based on gold/silver core shell nanoparticles (Au@Ag NPs) for a simple, inexpensive, instrument-free, and portable determination of cyanide by the naked eye. Au@Ag NPs immobilized on a paper channel were etched by cyanide ions so that a yellow color band length of Au@Ag NPs is proportional to a decrease in the cyanide concentration. Quantification is achieved by measuring color length, thus eliminating the need to differentiate hues and intensities by the user, and the processing data of each imaging device. Moreover, the paper-based headspace extraction was combined with the distance-based paper device to improve the sensitivity. The enrichment factor was found to be 30-fold and the linearity was found in the range 0.05−1 mg L−1. The naked eye detection limit was 10 μg L−1 where the World Health Organization (WHO) have regulated the maximum level of cyanide in drinking water as 70 μg L−1. Our proposed device also showed no interference from common cations and anions presenting in seawater and waste water including thiocyanate, chloride. Finally, our device has been successfully applied to determine cyanide ions in seawater, drinking water, tap water and wastewater providing satisfactory precision and accuracy.
