Highlighting extended-spectrum beta-lactamase-producing Klebsiella pneumoniae outbreak by routine genomic typing
F. Gravey,
S. Wilson,
A. Denisenko,
C. Lehoussel,
Marguerite Fines-Guyon,
S. Le Hello,
C. Jeanne-Leroyer
Affiliations
F. Gravey
Univ de Caen Normandie, Univ Rouen Normandie, INSERM DYNAMICURE UMR 1311, CHU Caen, Caen, France; CHU Caen, Departement of Microbiology, F-14000, Caen, France
S. Wilson
CHU Caen, Departement of Hospital Hygiene and Infection Control, F-14000, Caen, France
A. Denisenko
CHU Caen, Departement of Surgical Intensive Care Unit, F-14000, Caen, France
C. Lehoussel
Univ de Caen Normandie, Univ Rouen Normandie, INSERM DYNAMICURE UMR 1311, CHU Caen, Caen, France
Marguerite Fines-Guyon
CHU Caen, Departement of Microbiology, F-14000, Caen, France
S. Le Hello
Univ de Caen Normandie, Univ Rouen Normandie, INSERM DYNAMICURE UMR 1311, CHU Caen, Caen, France; CHU Caen, Departement of Microbiology, F-14000, Caen, France; CHU Caen, Departement of Hospital Hygiene and Infection Control, F-14000, Caen, France; Corresponding author. Normandie Univ, UNICAEN, UNIROUEN, CHU Caen Normandie, Department of Hospital Hygiene and Infection Control and Microbiology, Inserm UMR, 1311 DYNAMICURE, 14000, Caen, France.
C. Jeanne-Leroyer
Univ de Caen Normandie, Univ Rouen Normandie, INSERM DYNAMICURE UMR 1311, CHU Caen, Caen, France
Whole genome sequencing has become the gold standard for any microbiological investigations. Taking the opportunity to doing it prospectively and routinely allowed to detect undeclared outbreaks. Thanks to that, we investigated and ended a rare epidemic extended-spectrum beta-lactamase-producing Klebsiella pneumoniae ST584 strain on two intensive care units over a 4-month period.
