Revista da Sociedade Brasileira de Medicina Tropical (May 2019)

Detection of HIV-1 infections in blood donors during the pre-seroconversion window period in São Paulo, Brazil

  • Nanci Alves Salles,
  • Anna Shoko Nishiya,
  • Suzete Cleusa Ferreira,
  • Vanderson Geraldo Rocha,
  • Alfredo Mendrone-Junior

DOI
https://doi.org/10.1590/0037-8682-0432-2018
Journal volume & issue
Vol. 52, no. 0

Abstract

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Abstract By decreasing the pre-seroconversion window period, nucleic acid testing (NAT) has improved the safety of blood products and reduced the risk of transfusion-transmitted infections. Between 2011 and 2017, NAT determinations for approximately 898,202 donations were performed at Fundação Pró-Sangue/Hemocentro de São Paulo (FPS-HSP). Three seronegative HIV-viremic donations were detected. The NAT yield rate per million donations was 3.34 for HIV, and the acute HIV-1 infections detected are described, followed by a brief review of the situation in Brazil.

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