Clonal genetic evolution at relapse of favorable-risk acute myeloid leukemia with NPM1 mutation is associated with phenotypic changes and worse outcomes

• Carmen Martínez-Losada,
• Juana Serrano-López,
• Josefina Serrano-López,
• Nelida I. Noguera,
• Eduardo Garza,
• Liliana Piredda,
• Serena Lavorgna,
• María Antonietta Irno Consalvo,
• Tiziana Ottone,
• Valentina Alfonso,
• Juan Ramón Peinado,
• María Victoria Garcia-Ortiz,
• Teresa Morales-Ruiz,
• Andrés Jérez,
• Ana María Hurtado,
• Pau Montesinos,
• José Cervera,
• Esperanza Such,
• Marian Ibañez,
• Amparo Sempere,
• Miguel Ángel Sanz,
• Francesco Lo-Coco,
• Joaquín Sánchez-García

Affiliations

Carmen Martínez-Losada

Hematology Department, Reina Sofía University Hospital/Maimonides Biomedical Research Institute of Córdoba (IMIBIC)/University of Córdoba, Spain

Juana Serrano-López

Hematology Department, Reina Sofía University Hospital/Maimonides Biomedical Research Institute of Córdoba (IMIBIC)/University of Córdoba, Spain

Josefina Serrano-López

Hematology Department, Reina Sofía University Hospital/Maimonides Biomedical Research Institute of Córdoba (IMIBIC)/University of Córdoba, Spain

Nelida I. Noguera

Department of Biomedicine and Prevention, “Tor Vergata” University, Rome, Italy;Laboratory of Neuro-Oncohematology, Santa Lucia Foundation, Rome, Italy

Eduardo Garza

Laboratorios Dr. Moreira, Monterrey, Mexico

Liliana Piredda

Department of Biomedicine and Prevention, “Tor Vergata” University, Rome, Italy

Serena Lavorgna

Department of Biomedicine and Prevention, “Tor Vergata” University, Rome, Italy

María Antonietta Irno Consalvo

Department of Biomedicine and Prevention, “Tor Vergata” University, Rome, Italy

Tiziana Ottone

Department of Biomedicine and Prevention, “Tor Vergata” University, Rome, Italy

Valentina Alfonso

Department of Biomedicine and Prevention, “Tor Vergata” University, Rome, Italy

Juan Ramón Peinado

Medical Sciences Department, Faculty of Medicine/University of Ciudad Real (UCLM), Spain

María Victoria Garcia-Ortiz

Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/University of Córdoba/Reina Sofia University Hospital, Spain

Teresa Morales-Ruiz

Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/University of Córdoba/Reina Sofia University Hospital, Spain

Andrés Jérez

Hematology Department University Hospital Morales Meseguer-IMIB, Spain

Ana María Hurtado

Hematology Department University Hospital Morales Meseguer-IMIB, Spain

Pau Montesinos

Hematology Department, Hospital Universitari I Politècnic La Fe, Valencia, Spain

José Cervera

Hematology Department, Hospital Universitari I Politècnic La Fe, Valencia, Spain

Esperanza Such

Hematology Department, Hospital Universitari I Politècnic La Fe, Valencia, Spain

Marian Ibañez

Hematology Department, Hospital Universitari I Politècnic La Fe, Valencia, Spain

Amparo Sempere

Hematology Department, Hospital Universitari I Politècnic La Fe, Valencia, Spain

Miguel Ángel Sanz

Hematology Department, Hospital Universitari I Politècnic La Fe, Valencia, Spain

Francesco Lo-Coco

Department of Biomedicine and Prevention, “Tor Vergata” University, Rome, Italy;Laboratory of Neuro-Oncohematology, Santa Lucia Foundation, Rome, Italy

Joaquín Sánchez-García

Hematology Department, Reina Sofía University Hospital/Maimonides Biomedical Research Institute of Córdoba (IMIBIC)/University of Córdoba, Spain