Brazilian Journal of Psychiatry (Sep 2006)

Adult mood disorders and childhood psychological trauma

  • Maria Lucrécia Scherer Zavaschi,
  • Maria Elisa Graeff,
  • Marcos Tatit Menegassi,
  • Victor Mardini,
  • Denise Winkler Simões Pires,
  • Rafael Homem de Carvalho,
  • Luis Augusto Rohde,
  • Cláudio Laks Eizirik

DOI
https://doi.org/10.1590/s1516-44462006000300008
Journal volume & issue
Vol. 28, no. 3
pp. 184 – 190

Abstract

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OBJECTIVE: To evaluate the association between adult mood disorders and childhood psychological trauma in a developing country. METHOD: Adults with and without mood disorders were assessed in a case-control study using the Mini International Neuropsychiatric Interview. Assessment of childhood trauma included physical and sexual abuse, frequent exposure to violence, and parental loss. RESULTS: In two independent multivariate analyses, after adjusting for potential confounding factors, we found a higher odds ratio for frequent exposure to violence in the community (p = .037) and for physical abuse by parents or caregivers during childhood/adolescence (p = .012) in the group with mood disorders than in the control group. In secondary analyses splitting the mood disorder group in two subgroups (manic episode, and major depressive episodes/ dysthymia), only manic patients showed significantly higher rates of frequent exposure to violence in the community (p = 0.01) and physical abuse during childhood (p = 0.02) than did patients in the control group. In addition, maniac patients had significantly higher rates of sexual abuse than did controls (p = .03). CONCLUSIONS: Our findings document an association between violence during childhood and adult mood disorders, especially for manic patients, in a developing country.

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