Tadalafil treatment for fetuses with early-onset growth restriction: a protocol for a multicentre, randomised, placebo-controlled, double-blind phase II trial (TADAFER IIb)

• Hiroaki Tanaka,
• Yasuhiro Tanaka,
• Yoichi Aoki,
• Masayuki Endo,
• Tomoaki Ikeda,
• Shintaro Maki,
• Masafumi Nii,
• Kayo Tanaka,
• Satoshi Tamaru,
• Toru Ogura,
• Yuki Nishimura,
• Tomomi Kotani,
• Akihiko Sekizawa,
• Masahiko Nakata,
• Koji Nakamura,
• Kenji Nagao,
• Ichiro Yasuhi,
• Hiroshi Kawamura,
• Sho Takakura,
• Mayumi Kotera,
• Takafumi Ushida,
• Norihiko Kikuchi,
• Tadatsugu Kinjo,
• Mayumi Takano,
• Sachie Suga,
• Michi Kasai,
• Osamu Yasui,
• Yuka Maegawa,
• Shigeru Aoki,
• Yoshio Yoshida

Affiliations

Hiroaki Tanaka

1 Department of Hematology, Asahi General Hospital, Asahi, Chiba, Japan

Yasuhiro Tanaka

1 Otorhinolaryngology, Dokkyo Medical University Saitama Medical Center, Koshigaya, Saitama, Japan

Yoichi Aoki

Obstetrics and Gynecology, University of the Ryukyus, Nishihara, Japan

Masayuki Endo

1 Department of Obstetrics and Gynecology, Osaka University, Suita, Osaka, Japan

Tomoaki Ikeda

16 Department of Obstetrics and Gynecology, Mie University, Tsu, Japan

Shintaro Maki

1 Department of Obstetrics and Gynecology, Mie University Graduate School of Medicine, Tsu, Japan

Masafumi Nii

1 Department of Obstetrics and Gynecology, Mie University Graduate School of Medicine, Tsu, Japan

Kayo Tanaka

1 Department of Obstetrics and Gynecology, Mie University Graduate School of Medicine, Tsu, Japan

Satoshi Tamaru

2 Clinical Research Support Center, Mie University Hospital, Tsu, Japan

Toru Ogura

2 Clinical Research Support Center, Mie University Hospital, Tsu, Japan

Yuki Nishimura

2 Clinical Research Support Center, Mie University Hospital, Tsu, Japan

Tomomi Kotani

4 Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, Nagoya, Japan

Akihiko Sekizawa

5 Department of Obstetrics and Gynecology, Showa University Graduate School of Medicine, Tokyo, Japan

Masahiko Nakata

6Toho University, Tokyo, Japan

Koji Nakamura

Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka;

Kenji Nagao

12 Department of Obstetrics and Gynecology, Yokkaichi Municipal Hospital, Yokkaichi, Mie, Japan

Ichiro Yasuhi

Department of Obstetrics and Gynecology, National Hospital Organization Nagasaki Medical Center, Nagasaki, Japan.

Hiroshi Kawamura

1 Heart Rhythm Center, Okayama Heart Clinic, Okayama, Japan

Sho Takakura

1 Department of Obstetrics and Gynecology, Mie University Graduate School of Medicine, Tsu, Mie, Japan

Mayumi Kotera

2 Clinical Research Support Center, Mie University Hospital, Tsu, Mie, Japan

Takafumi Ushida

3 Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan

Norihiko Kikuchi

4 Department of Obstetrics and Gynecology, Shinshu University Graduate School of Medicine, Matsumoto, Nagano, Japan

Tadatsugu Kinjo

5 Department of Obstetrics and Gynecology, University of the Ryukyus, Nakagami-gun, Okinawa, Japan

Mayumi Takano

7 Department of Obstetrics and Gynecology, Toho University Faculty of Medicine, Otaku, Tokyo, Japan

Sachie Suga

9 Department of Obstetrics and Gynecology, National Hospital Organization Nagasaki Medical Center, Omura, Nagasaki, Japan

Michi Kasai

10 Perinatal Center for Maternity and Neonate, Yokohama City University Medical Center, Yokohama, Kanagawa, Japan

Osamu Yasui

11 Department of Obstetrics and Gynecology, Showa University Graduate School of Medicine, Shinagawa-ku, Tokyo, Japan

Yuka Maegawa

13 Department of Obstetrics and Gynecology, Mie Chuo Medical Center, Tsu, Mie, Japan

Shigeru Aoki

10 Perinatal Center for Maternity and Neonate, Yokohama City University Medical Center, Yokohama, Kanagawa, Japan

Yoshio Yoshida

6 Department of Obstetrics and Gynecology, Fukui University Graduate School of Medicine, Fukui, Japan