Binding of phosphatidylcholine-14C to glass

Abstract

Lecithin-14C was found to bind to Pyrex glass. The percentage bound varied with different organic solvents, being greatest in dioxane solution. Thorough treatment of the glass with dimethyldichlorosilane prevents the binding, which suggests that charge-charge interactions are involved.

Keywords

• fritted glass
• silanized glassware
• phospholipid adsorption