Nature Communications (Jan 2023)

Transformer for one stop interpretable cell type annotation

  • Jiawei Chen,
  • Hao Xu,
  • Wanyu Tao,
  • Zhaoxiong Chen,
  • Yuxuan Zhao,
  • Jing-Dong J. Han

DOI
https://doi.org/10.1038/s41467-023-35923-4
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 14

Abstract

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Developing computational tools for interpretable cell type annotation in scRNA-seq data remains challenging. Here the authors propose a Transformer-based model for interpretable annotation transfer using biologically understandable entities, and demonstrate its performance on large or atlas datasets.